Human Research Protection Program


As an institution, UIUC must ensure the protection of human subjects in research by maintaining policies and procedures compliant with federal regulations and other applicable laws.


Elements of the HRPP generally include:

  • IRB review
  • Financial conflict of interest review and management
  • HIPAA Privacy review
  • Training and Qualifications review
  • State law and institutional requirements review
  • Other Ancillary review (e.g. Institutional Biosafety Committee, Radiation Safety Committee)

Relying on an External IRB

Even in cases where an external IRB is used (often referred to as “relying” on another IRB), UIUC is still required to perform the remaining HRPP responsibilities.

OPRS manages the HRPP review process regardless of whether a UIUC IRB is used or an external IRB is used. Learn more about the HRPP review process while using an external IRB:

More about relying on an external IRB



AAHRPP Accreditation

The UIUC Human Research Protection Program has been awarded full accreditation by the Association for the Accreditation of Human Research Protection Programs. AAHRPP promotes high-quality, ethically sound research through an accreditation process that helps organizations worldwide strengthen their HRPP.

AAHRPP uses a voluntary, peer-driven educational model to ensure that HRPPs meet rigorous standards for quality and protection. AAHRPP accreditation offers assurances — to research participants, researchers, sponsors, government regulators, and the general public — that an HRPP is focused first and foremost on excellence.