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2022 Holiday Information 

Beginning Friday, December 23, 2022, OPRS will be closed for holiday break. The office will resume regular working hours on January 3rd. To ensure your submission is pre-reviewed before break, please submit by Friday, December 9th at 5pm. Anything received after 5pm on Friday, December 9th will be logged in for pre-review on Tuesday, January 3, 2023. Please note that submission by December 9th, 2022 does not guarantee convened board review before the holiday break.  

What's Happening

Upcoming Meetings

December 13, 2022

Next Social Behavioral IRB meeting

December 8, 2022

Next Biomedical IRB meeting

See all meeting dates

Exempt Form Update

Effective November 1, 2022, all human subject research applications must be submitted on the “Protocol Form”.  Any projects submitted on the old “Exempt Form” will no longer be accepted.  OPRS will continue to make Exempt determinations for all eligible protocols. Exempt forms submitted to OPRS prior to November 1, 2022, will be reviewed.  

As investigators are expected to maintain full protocols for all human subject research according to regulation, regardless of risk level, utilizing one protocol form for submission will allow investigators to submit their protocol information more easily to OPRS.  This update will also help streamline the processes as we prepare to transition to the new electronic submission system.

Required Training

Starting October 1, 2022, OPRS will only accept the Core IRB Training course as our minimum requirement. Protocols received after October 1, 2022 that lack Core IRB Training completion dates for all investigators will not be approved until the required training has been completed. To access and view training completions, please visit the OVCRI training portal.

About the IRB

All research involving human subjects that is conducted at or sponsored by the University of Illinois at Urbana-Champaign, whether funded or unfunded and whether conducted by Illinois faculty or others, must comply with applicable policies for the protection of human subjects.


Research participants: please contact us with any questions and/or concerns you may have regarding your role in a research study. Comments may be made confidentially. 

You may also follow the link below to complete an anonymous survey. If you would like OPRS to follow up, there is an option to provide your contact information.


Useful Links

Office of the Vice Chancellor for Research and Innovation

Research Integrity and Ethics

Graphic that displays the OPRS workflow

What is the OPRS?

The Office for the Protection of Research Subjects (OPRS), while performing administrative functions of the Institutional Review Board (IRB), serves as the official oversight office for human subject research at Illinois. The office is the central point of contact for investigators, research subjects, and regulatory agencies. OPRS organizes and documents the IRB review process, monitors research regulations, produces educational resources for faculty and staff, and provides assurance that the Urbana campus is in compliance with federal, state, and campus policies. Contact OPRS.